Asteracantha longifolia (L.) Nees, Acanthaceae: química, usos tradicionais e medicinais e suas atividades farmacológicas – uma revisão. The aim of the present study was to study the effect of seeds of Asteracantha longifolia on the sexual behaviour of male albino rats. The ethanolic extract of. Anaemia is a common nutritional disorder, mainly caused by iron deficiency. Asteracantha longifolia Nees (Family. Acanthaceae) is a source of the ayurvedic .

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Department of Pharmaceutical Sciences, Dr.

Nees, Acanthaceae, is a source of the ayurvedic drug, ‘Kokilaaksha’ and the Unani drug, Talimakhana. The seeds are acrid, bitter, aphrodisiac, tonic, sedative, used for diseases of the sateracantha. The plant is known to possess antitumor, hypoglycemic, aphrodisiac, antibacterial, free radical scavenging and lipid peroxidation, hepatoprotective and haematopoietic activity.

It contains lupeol, stigmasterol, butelin, fatty acids, and alkaloids. The present review article is focused on phytochemical, pharmacological and other important aspects of Talimakhana. Astercantha longifolia, Rasayana, aphrodisiac, tonic. Rasayana is the special category of the drugs of Indian system of medicine Ayurveda.

The word Rasayana is composed of two words ‘Rasa’ meaning elixir and ‘Ayana’ meaning house. The word therefore signifies property of the plant that helps to rejuvenate the system.

Asteracantha Longifolia Herb Uses, Benefits, Cures, Side Effects, Nutrients

Many plants have been broadly used as ‘Rasayana’ drugs in Ayurveda for the management of neurodegenerative diseases, as rejuvenators, immunomodulators, aphrodisiac and tonic Thakur et al. The Asteracantha longioflia L. They are also constituent of ayurvedic formulation “Strirativallabhpugpak” and “Rativardhanyog” described in ancient text to improve sexual behaviour and as a general tonic Vaidya, The present article includes the detailed exploration of pharmacological and phytochemical properties of A.

It is a spiny, stout, annual herb, common in water logged places. Leaves subsessile, oblong-lanceloate or linear lanceolate, spines yellowish brown, cm long, Flower yellowish brown, fruit two celled, linear oblong, compressed about 8 cm long, pointed, seeded Figure 1. Seed ovate, flat or compressed, 0.

Not more than 2. Not more than 8. Not more than 3. Not more than The whole plant, roots, seeds, and ashes of the plant are extensively used in traditional system of medicine for various ailments like rheumatism, inflammation, jaundice, hepatic obstruction, pain, urinary infections, oedema and gout. It is classified in ayurvedic system as seethaveeryam, mathuravipaka and used for the treatment of premeham diabetesathisaram dysentry etc Nadkarni, ; Chopra et al.

Ethanolic extract Al Eth of aerial parts of A. Longifola is also decrease in thiobarbituric acid reactive substances TBARS and hydroperoxide in both asterracantha and kidney. Al Eth treated rats also showed decreased lipid peroxidation that is associated with increased activity of superoxide dismutase SOD and catalase Vijayakumar et al. Administration of aqueous extract of A.


However, the plant extract had no effect on the gluconeogenic capacity of the kidney or intestinal glucose absorption Fernando et al. The aqueous extract of whole plant and root of A.

Effect of Asteracantha longifolia seeds on the sexual behaviour of male rats.

Petroleum ether extract of A. Later they also reported that the slurry, aqueous extract and ethanolic extract of whole plant powder showed hepatoprotective effect against galactosamine induced hepatotoxicity Shailajan et al.

Chloroform and alcoholic extracts of A. Methanol extracts of A.

Petroleum ether, chloroform, alcoholic and aqueous azteracantha of leaves of Hygrophila spinosa longifo,ia significant anthelmintic activity, both alcoholic and chloroform extracts showed significant antibacterial activity as compared to other extracts Patra et al.

Petroleum ether extract of lonigfolia from A. In anemic male albino rats, the extract significantly increased haemoglobin, haematocrit and RBC count Gomes et al. Petroleum ether and chloroform extract of leaves show haematopoietic activity as it significantly increases erythrocyte count, leukocyte count, and haemoglobin count Pawar et al.

Methanol extract of seed shows inhibition of hepatocarcinogenesis in Wistar rats. Petroleum ether extract from A. Extract suppressed significantly the tumor fluid volume at the end of three weeks experiment. It also repressed the rapid increase of bodyweight of tumor bearing mice Mazumdar et al. The ethanolic extract of seeds shows androgenic as well as improvement of sexual behaviour of rat in dose dependent manner, it also improve the histoarchitecture of testis and increase the concentration of sperm count in epididymis and also increase testosterone level Chauhan et al.

The phytochemical investigation of the A. Aerial parts of A. Misra et al isolated the two aliphatic esters oxo-hentriacontanyl acetate 4and methyl 8-n-hexyltetracosanoate, 5 and betulin from the aerial parts of A. The HPTLC estimation of lupeol and sitosterol in various part like root, leaves, seeds and stems was reported in solvent system toluene: The whole plant contains lupeol, stigmasterol, an isoflavone glycoside, an alkaloid and small quantities of uncharacterized bases.

Also, amino acids histidine, lysine and phenyl-alanine have been detected in the seeds. From the plant collected from Saharanpur, lupeol, betulin and stigmasterol isolated; betulin was found to be absent in aerial parts and stigmasterol in roots Gupta et al.

Erythropoietic activity of Asteracantha longifolia (Nees.) in rats.

The methanolic extract of leaves contain phenolic and flavonoid shows promising antioxidant activity Sawadogo et al. Aqueous extract of leaves of A. Petroleum ether extract of root potentiated the sedative-hypnotic action of chlorpromazine, diazepam, pentobarbitone, chlordiazepoxide and protected against strychine-induced convulsions Mazumder et al. Aqueous extract of root and leaves cure patient suffering from dropsy Jayesingha, Ethanolic extract asteracanyha whole asteracantah showed diuretic effects in rats Sarfaraj Hussain et al.

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Plants having spines, having perennial root stocks; bluish-purple 2-lipped astrracantha leaves – sessile, multichambered thick-walled sclerotic cell, among the epidermal cells of midrib, large flat bunch-shaped calcium carbonate crystals and needle-shaped calcium oxalate crystals in the epidermal cells of lamina and in the cortical cells of midrib respectively; stomata-caryophyllaceous; stomatal index on upper surface: Speman a polyherbal formulation containig A.

High Plant regeneration frequency in A. Protein and total soluble sugar contents were maximum during organogenesis and multiple shoot induction phase compared with non-organogenic callus and root induction phase. Esterase and catalase activities ssteracantha maximum during organogenic differentiation, while activities were minimum at non-differentiated callus stages.

Peroxidase activities were higher during rhizogenesis whereas acid phosphatase activities were high xsteracantha organogenesis and declined during rhizogenesis Panigrahi et al. Further researches in view of fulfilling the need of standardization for the various constituents and extracts are desired.

Efficacy and safety of speman in patients with oligospermia: An open clinical study. Indian J Clinical Practice Anti-tumor promoting activity of Asteracantha longifolia against experimental hepatocarcinogenesis in rats.

Erythropoietic activity of Asteracantha longifolia (Nees.) in rats.

Food Chem Toxicol Balraj P, Nagarajan S Apigenin 7- O -glucuronide from the flowers of Asteracantha longifolia. Indian J Pharma Sci Apigenin 7-O-glucuronide from the flowers of Asteracantha longifolia.

Basu N, Rakhit S a. Investigation of the seeds of Asteracantha longifolia Nees. Indian J Pharmacy Basu NK, Asteracantga S b. Effect of Asteracantha longifolia seeds on sexual behavior of male rats. Nat Prod Res Effect of Rasayana herbs on pituitary gonadal axis.

Europ J Integr Med 2: Glossary of Indian Medicinal Plants.

Choudhary BK, Bandyopdhyay Important of mineral content and medicinal properties of Moringa oleifera and Hygrophila auriculata. Datta PC, Das M Pharmacognostic study of root, leaf and seed of Asteracantha longifolia Nees.

Dasgupta N, De B Antioxidant activity of some leafy vegetables of India: A preliminary investigation of the possible hypoglycaemic activity of Asteracantha longifolia.

Effect of Artocarpus heterophyllus and Asteracantha longifolia on glucose tolerance in normal human subjects and in maturity-onset diabetic patients.

Extra pancreatic actions of Hygrophila longifolia. An investigation of oil from seed of Hygrophila spinosa. Haematinic effect of Hygrophila spinosa T. Anderson on experimental rodents.

Indian J Exp Biol Chemical examination of Asteracantha longifolia. J Nat Prod Quality standard of Indian Medicinal Plants. Indian Council of Medical researchNew Delhi.

Protective effect of Asteracantha longifolia extract in mouse liver injury induced by carbon tetrachloride and paracetamol. J Pharm Pharmacol On Hygrophila spinosa Vel Asteracantha longifolia.